Our paper entitled “Motorized template for MRI-guided focal cryoablation of prostate cancer” has been published in IEEE Transactions on Medical Robotics and Bionics. The paper presents a new motorized template device to assist a physician in placing ablation probes into the prostate under magnetic resonance imaging (MRI)-guidance for focal ablation. The device, developed as part of our collaboration with Physical Sciences Inc., combined a motorized tilting grid template with insertion depth sensing capabilities, enabling the physician to place the cryo-needles precisely in the desired location.
Our in-vivo study (swine) showed that the insertion depth feedback improved the 3D targeting accuracy compared to the conventional insertion technique (7.4 mm vs. 11.2 mm, p=0.04). All three cases achieved full iceball coverage without repositioning the cryo-needles. The results demonstrate the advantages of the motorized tilting mechanism, real-time insertion depth feedback, and the feasibility of the proposed workflow for MRI-guided focal cryoablation of prostate cancer.
Reference
- Moreira P, Grimble J, Bernardes MC, Iftimia N, Levesque VM, Foley L, Tuncali K, Tokuda J, Park J. Motorized template for MRI-guided focal cryoablation of prostate cancer. IEEE Trans Med Robot Bionics. 2023;5(2):335–342. doi:10.1109/tmrb.2023.3272025 PMID: 37312886. PMCID: PMC10259684.
Grant Support
This study is supported in part by the National Institutes of health (R43EB032676, P41EB028741, R01CA235134, R01EB020667).
